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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73912861266d6aca2bd77b85445fa70ce96fcde3e16f02303b2364316e43f0ca' 
  AND token = 'u/DuRXmbb6lceTecY4pFEnoag9UfJnuQu+VzemYhSMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}