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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2682da6d5ab15d6788171037ee39dc0cb257742e1a5c51403b8bfaeb7b6a8436' 
  AND token = 'nIEMyUs8k2hhcQhCa5wfTnb4LF5EDRPTt3/YRn+/8mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}