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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159181897b90d2f36610eb7f9ab4ee09948843e7ac5978ed1aa1415e63f81b71' 
  AND token = 's+Zx9U7a61j3yp8NsVzn6Tx5Py5lHmghIRTMGlLExZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}